Search results for "genetics [Transcriptome]"
showing 10 items of 3033 documents
Alternative splicing regulation by Muscleblind proteins: from development to disease.
2011
Regulated use of exons in pre-mRNAs, a process known as alternative splicing, strongly contributes to proteome diversity. Alternative splicing is finely regulated by factors that bind specific sequences within the precursor mRNAs. Members of the Muscleblind (Mbl) family of splicing factors control critical exon use changes during the development of specific tissues, particularly heart and skeletal muscle. Muscleblind homologs are only found in metazoans from Nematoda to mammals. Splicing targets and recognition mechanisms are also conserved through evolution. In this recognition, Muscleblind CCCH-type zinc finger domains bind to intronic motifs in pre-mRNA targets in which the protein can e…
A doubly bridged isodicyclopentadienyl zirconium complex: bis{N-(3,5-dimethylphenyl)-N-[(η5-isodicyclopentadien-2-yl)dimethylsilyl]amido-κN}zirconium…
2002
Transmetallation of the dilithium salt of (3,5-dimethyphenylamino)(isodicyclopentadienyl)dimethylsilane by treatment with zirconium tetrachloride in a 2:1 ratio leads to the substitution of all four chloride ligands. With the applied stoichiometry, the title complex, [Zr(C(20)H(25)NSi)(2)].C(4)H(10)O, was obtained and crystallized from diethyl ether. X-ray diffraction characterization showed that both isodicyclopentadienyl ligands (alternatively called 4,5,6,7-tetrahydro-4,7-methano-1H-indene) are complexed to the metal on their exo face in a completely stereoselective manner and that they are eta(5)-bonded to the Zr atom.
Introduction. Ecological immunology.
2009
12 pages; International audience; An organism's fitness is critically reliant on its immune system to provide protection against parasites and pathogens. The structure of even simple immune systems is surprisingly complex and clearly will have been moulded by the organism's ecology. The aim of this review and the theme issue is to examine the role of different ecological factors on the evolution of immunity. Here, we will provide a general framework of the field by contextualizing the main ecological factors, including interactions with parasites, other types of biotic as well as abiotic interactions, intraspecific selective constraints (life-history trade-offs, sexual selection) and popula…
Carotenoid-based colour of acanthocephalan cystacanths plays no role in host manipulation.
2009
Manipulation by parasites is a catchy concept that has been applied to a large range of phenotypic alterations brought about by parasites in their hosts. It has, for instance, been suggested that the carotenoid-based colour of acanthocephalan cystacanths is adaptive through increasing the conspicuousness of infected intermediate hosts and, hence, their vulnerability to appropriate final hosts such as fish predators. We revisited the evidence in favour of adaptive coloration of acanthocephalan parasites in relation to increased trophic transmission using the crustacean amphipodGammarus pulexand two species of acanthocephalans,Pomphorhynchus laevisandPolymorphus minutus. Both species show car…
Multidimensionality in host manipulation mimicked by serotonin injection.
2014
Manipulative parasites often alter the phenotype of their hosts along multiple dimensions. ‘Multidimensionality’ in host manipulation could consist in the simultaneous alteration of several physiological pathways independently of one another, or proceed from the disruption of some key physiological parameter, followed by a cascade of effects. We compared multidimensionality in ‘host manipulation’ between two closely related amphipods, Gammarus fossarum and Gammarus pulex, naturally and experimentally infected with Pomphorhynchus laevis (Acanthocephala), respectively. To that end, we calculated in each host–parasite association the effect size of the difference between infected and uninfect…
Inverse Tone Mapping Based upon Retina Response
2014
International audience; The development of high dynamic range (HDR) display arouses the research of inverse tone mapping methods, which expand dynamic range of the low dynamic range (LDR) image to match that of HDR monitor. This paper proposed a novel physiological approach, which could avoid artifacts occurred in most existing algorithms. Inspired by the property of the human visual system (HVS), this dynamic range expansion scheme performs with a low computational complexity and a limited number of parameters and obtains high-quality HDR results. Comparisons with three recent algorithms in the literature also show that the proposed method reveals more important image details and produces …
Hybrid multiple diffraction in semipolar wurtzite materials: (\bf 01\overline{1}2)-oriented ZnMgO/ZnO heterostructures as an illustration
2017
X-ray diffraction has been widely used to characterize the structural properties (strain and structural quality) of semiconductor heterostructures. This work employs hybrid multiple diffraction to analyzer-oriented Zn1−xMgxO layers grown by molecular beam epitaxy on ZnO substrates. In such a low-symmetry material system, additional features appear in symmetric reflection scans, which are described as arising from hybrid multiple diffraction. First, the Bragg conditions necessary for these high-order processes to occur are introduced and applied to explain all the observed satellite reflections, identify the planes that contribute and computea priorithe angles at which they are observed. Fur…
Une chrysomèle contre l'ambroisie, est-ce réaliste ?
2016
Context - Despite intensive management practices carried out by stakeholders, common ragweed control is presently not sufficient to limit the spread of this annual invasive plant. Ali classical methods (mowing, chemical weeding, etc.) are limited in terms of efficiency. ln order to achieve a better management in the different habitats occupied by the plant, it is necessary to design innovative methods that could increase contra efficiency. The recent accidental introduction of a ragweed natural enemy in ltalia raises the question of the use of biological control agents. Could the regulation by a new phytophagous insect be considered as an integrated way of management in order to reduce the …
Permineralized coniferophytes from the Autun Basin: specimens from two new localities of Renault zone 3
2015
International audience; Four zones yielding silicified plant remains have been recognized in the Autun Basin by Renault (1893-1896). Zones 2, 3 and 4, characterized by Autunian plants, correspond to the successive formations of Igornay and Muse (lower Autunian), and Surmoulin-Millery (upper Autunian). Their paleobotanical content, together with that preserved as adpressions in the same formations, document paleofloral changes on the western side of the Tethys within a time interval extending from the latest Ghzelian (uppermost Pennsylvanian) to the early Sakmarian (lower Permian) (Broutin et al. 1999). The analyses realized so far indicate a progressive replacement of wetland plants by taxa…
La lutte biologique contre l'ambroisie à feuille d'armoise illustrée par l'exemple d'Ophraella communa : quels intérêts et quelles limites
2016
Common ragweed (Ambrosia artemisiifolia) was introduced in France over 150 years ago and its spreading across France now seems inexorable. The specific biology of this summer annual creates new problems for the managers of the various habitats where the plant can be found. The reduced possibility, or even the impossibility, to use traditional control means in certain environment conditions brings managers to consider biological control as one of the few possible means for slowing down the spread, or even pushing back the distribution area, of this invasive and allergenic plant. With Ophraella communa as an example, a reflection is presented on the benefit-risk balance of the introduction of…